Targeting of De Novo DNA Methylation Throughout the Oct-4 Gene Regulatory Region in Differentiating Embryonic Stem Cells

Differentiation of embryonic stem (ES) cells is accompanied by silencing of the Oct-4 gene and de novo DNA methylation of its regulatory region. Previous studies have focused on the requirements for promoter region methylation. We therefore undertook to analyse the progression of DNA methylation of...

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Detalles Bibliográficos
Autores principales: Athanasiadou, Rodoniki, de Sousa, Dina, Myant, Kevin, Merusi, Cara, Stancheva, Irina, Bird, Adrian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848578/
https://www.ncbi.nlm.nih.gov/pubmed/20376339
http://dx.doi.org/10.1371/journal.pone.0009937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848578/
https://www.ncbi.nlm.nih.gov/pubmed/20376339
http://dx.doi.org/10.1371/journal.pone.0009937

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