Cargando…

Raltegravir Is a Potent Inhibitor of XMRV, a Virus Implicated in Prostate Cancer and Chronic Fatigue Syndrome

BACKGROUND: Xenotropic murine leukemia-related retrovirus (XMRV) is a recently discovered retrovirus that has been linked to human prostate cancer and chronic fatigue syndrome (CFS). Both diseases affect a large fraction of the world population, with prostate cancer affecting one in six men, and CFS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Singh, Ila R., Gorzynski, John E., Drobysheva, Daria, Bassit, Leda, Schinazi, Raymond F.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848589/ https://www.ncbi.nlm.nih.gov/pubmed/20376347 http://dx.doi.org/10.1371/journal.pone.0009948

Ejemplares similares

No Evidence for XMRV Nucleic Acids, Infectious Virus or Anti-XMRV Antibodies in Canadian Patients with Chronic Fatigue Syndrome
por: Steffen, Imke, et al.
Publicado: (2011)

Failure to Detect the Novel Retrovirus XMRV in Chronic Fatigue Syndrome
por: Erlwein, Otto, et al.
Publicado: (2010)

Jak Inhibitors Modulate Production of Replication-Competent Zika Virus in Human Hofbauer, Trophoblasts, and Neuroblastoma cells
por: Gavegnano, Christina, et al.
Publicado: (2017)

XMRV Discovery and Prostate Cancer-Related Research
por: Kang, David E., et al.
Publicado: (2011)

The effects of XMRV gene expression on the mouse prostate
por: Rauch, Daniel, et al.
Publicado: (2011)

Studies on the Efficacy, Potential Cardiotoxicity and Monkey Pharmacokinetics of GLP-26 as a Potent Hepatitis B Virus Capsid Assembly Modulator
por: Hurwitz, Selwyn J., et al.
Publicado: (2021)

Absence of XMRV and Closely Related Viruses in Primary Prostate Cancer Tissues Used to Derive the XMRV-Infected Cell Line 22Rv1
por: Das Gupta, Jaydip, et al.
Publicado: (2012)

Susceptibility of the human retrovirus XMRV to antiretroviral inhibitors
por: Smith, Robert A, et al.
Publicado: (2010)

XMRV replicates preferentially in mucosal sites in vivo: Relevance to XMRV transmission?
por: Villinger, Francois, et al.
Publicado: (2011)

Mechanism for XMRV neurotoxicity
por: Vaughan, Andrew E, et al.
Publicado: (2011)

No evidence of XMRV in prostate cancer cohorts in the Midwestern United States
por: Sakuma, Toshie, et al.
Publicado: (2011)

Approaches to hepatitis C treatment and cure using NS5A inhibitors
por: Kohler, James J, et al.
Publicado: (2014)

Assessment of a Computational Approach to Predict Drug Resistance Mutations for HIV, HBV and SARS-CoV-2
por: Patel, Dharmeshkumar, et al.
Publicado: (2022)

Lack of evidence for xenotropic murine leukemia virus-related virus(XMRV) in German prostate cancer patients
por: Hohn, Oliver, et al.
Publicado: (2009)

No Biological Evidence of XMRV in Blood or Prostatic Fluid from Prostate Cancer Patients
por: Mendoza, Ramon, et al.
Publicado: (2012)

Origin of XMRV and its Demise as a Human Pathogen Associated with Chronic Fatigue Syndrome
por: Hohn, Oliver, et al.
Publicado: (2011)

No Evidence for XMRV in German CFS and MS Patients with Fatigue Despite the Ability of the Virus to Infect Human Blood Cells In Vitro
por: Hohn, Oliver, et al.
Publicado: (2010)

No Evidence for Infection of UK Prostate Cancer Patients with XMRV, BK Virus, Trichomonas vaginalis or Human Papilloma Viruses
por: Groom, Harriet C. T., et al.
Publicado: (2012)

Downregulation of APOBEC3G by xenotropic murine leukemia-virus related virus (XMRV) in prostate cancer cells
por: Dey, Abhinav, et al.
Publicado: (2011)

No association between XMRV or related gammaretroviruses in Australian prostate cancer patients
por: Rezaei, Simin D, et al.
Publicado: (2013)

Of Mice and Men: On the Origin of XMRV
por: van der Kuyl, Antoinette Cornelia, et al.
Publicado: (2011)

Immune correlates of XMRV infection
por: Lombardi, Vincent, et al.
Publicado: (2011)

XMRV infection in human diseases
por: Erlwein, Otto, et al.
Publicado: (2011)

XMRV as a Human Pathogen?
por: Wainberg, Mark A., et al.
Publicado: (2011)

Crystal structure of xenotropic murine leukaemia virus-related virus (XMRV) ribonuclease H
por: Kim, Ju Hee, et al.
Publicado: (2012)

Raltegravir: first in class HIV integrase inhibitor
por: Temesgen, Zelalem, et al.
Publicado: (2008)

Xenotropic murine leukemia virus-related virus (XMRV) in prostate cancer cells likely represents a laboratory artifact
por: Yang, Jiawen, et al.
Publicado: (2011)

Raltegravir monohydrate
por: Yamuna, Thammarse S., et al.
Publicado: (2013)

The saga of XMRV: a virus that infects human cells but is not a human virus
Publicado: (2014)

The saga of XMRV: a virus that infects human cells but is not a human virus
por: Arias, Maribel, et al.
Publicado: (2014)

Development of XMRV producing B Cell lines from lymphomas from patients with Chronic Fatigue Syndrome
por: Ruscetti, Francis, et al.
Publicado: (2011)

From XMRV to HIV-1 and back
por: Coffin, John M
Publicado: (2011)

Cell line tropism and replication of XMRV
por: Devadas, Krishnakumar, et al.
Publicado: (2011)

Detection of a gammaretrovirus, XMRV, in the human population: Open questions and implications for xenotransplantation
por: Denner, Joachim
Publicado: (2010)

Clinical trial of raltegravir, an integrase inhibitor, in HAM/TSP
por: Enose‐Akahata, Yoshimi, et al.
Publicado: (2021)

Heme oxygenase-1 activation inhibits XMRV pathogenesis and carcinogenesis in prostate cancer cells
por: Dhawan, Subhash
Publicado: (2011)

A metagenomic approach to investigate the microbial causes of myalgic encephalomyelitis/chronic fatigue syndrome: moving beyond XMRV
por: Miller, Ruth R., et al.
Publicado: (2013)

Novel 1′-homo-N-2′-deoxy-α-nucleosides: synthesis, characterization and biological activity
por: Carnero, Alejandro, et al.
Publicado: (2020)

HIV resistance to raltegravir
por: Clavel, François
Publicado: (2009)

XMRV: usage of receptors and potential co-receptors
por: Haleyur Giri Setty, Mohan Kumar, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_5k3k8peqq4jiam5d9l31u30lva