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Natural Spike Trains Trigger Short- and Long-Lasting Dynamics at Hippocampal Mossy Fiber Synapses in Rodents

BACKGROUND: Synapses exhibit strikingly different forms of plasticity over a wide range of time scales, from milliseconds to hours. Studies on synaptic plasticity typically use constant-frequency stimulation to activate synapses, whereas in vivo activity of neurons is irregular. METHODOLOGY/PRINCIPA...

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Detalles Bibliográficos
Autores principales: Gundlfinger, Anja, Breustedt, Jörg, Sullivan, David, Schmitz, Dietmar
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848597/
https://www.ncbi.nlm.nih.gov/pubmed/20376354
http://dx.doi.org/10.1371/journal.pone.0009961