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Simultaneous determination of three major bioactive saponins of Panax notoginseng using liquid chromatography-tandem mass spectrometry and a pharmacokinetic study

BACKGROUND: Panax notoginseng saponins (PNS), the main active components of Radix Notoginseng, has been used for treating atherosclerosis, cerebral infarction, and cerebral ischemia. Ginsenosides Rg(1), ginsenoside Rb(1), and notoginsenoside R(1 )are the main contributors of biological activities, d...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Dang, Yunjie, Zhu, Chunyan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848657/
https://www.ncbi.nlm.nih.gov/pubmed/20331853
http://dx.doi.org/10.1186/1749-8546-5-12