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How predictive is the MMSE for cognitive performance after stroke?
Cognitive deficits are commonly observed in stroke patients. Neuropsychological testing is time-consuming and not easy to administer after hospital discharge. Standardised screening measures are desirable. The Mini-Mental State Examination (MMSE) is the test most widely applied to screen for cogniti...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848722/ https://www.ncbi.nlm.nih.gov/pubmed/20361295 http://dx.doi.org/10.1007/s00415-009-5387-9 |
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author | Bour, Ariane Rasquin, Sascha Boreas, Anita Limburg, Martien Verhey, Frans |
author_facet | Bour, Ariane Rasquin, Sascha Boreas, Anita Limburg, Martien Verhey, Frans |
author_sort | Bour, Ariane |
collection | PubMed |
description | Cognitive deficits are commonly observed in stroke patients. Neuropsychological testing is time-consuming and not easy to administer after hospital discharge. Standardised screening measures are desirable. The Mini-Mental State Examination (MMSE) is the test most widely applied to screen for cognitive deficits. Despite its broad use, its predictive characteristics after stroke have not been exhaustively investigated. The aim of this study was to determine whether the MMSE is able to adequately screen for cognitive impairment and dementia after stroke and whether or not the MMSE can predict further deterioration or recovery in cognitive function over time. To this end, we studied 194 first-ever stroke patients without pre-stroke cognitive deterioration who underwent MMSEs and neuropsychological test batteries at 1, 6, 12, and 24 months after stroke. The MMSE score 1 month after stroke predicted cognitive functioning at later follow-up visits. It could not predict deterioration or improvement in cognitive functioning over time. The cut-off score in the screening for 1 cognitive disturbed domain was 27/28 with a sensitivity of 0.72. The cut-off score in the screening for at least 4 impaired domains and dementia were 26/27 and 23/24 with a sensitivity of 0.82 and 0.96, respectively. The results indicated that the MMSE has modest qualities in screening for mild cognitive disturbances and is adequate in screening for moderate cognitive deficits or dementia in stroke patients 1 month after stroke. Poor performance on the MMSE is predictive for cognitive impairment in the long term. However, it cannot be used to predict further cognitive deterioration or improvement over time. |
format | Text |
id | pubmed-2848722 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Springer-Verlag |
record_format | MEDLINE/PubMed |
spelling | pubmed-28487222010-04-12 How predictive is the MMSE for cognitive performance after stroke? Bour, Ariane Rasquin, Sascha Boreas, Anita Limburg, Martien Verhey, Frans J Neurol Original Communication Cognitive deficits are commonly observed in stroke patients. Neuropsychological testing is time-consuming and not easy to administer after hospital discharge. Standardised screening measures are desirable. The Mini-Mental State Examination (MMSE) is the test most widely applied to screen for cognitive deficits. Despite its broad use, its predictive characteristics after stroke have not been exhaustively investigated. The aim of this study was to determine whether the MMSE is able to adequately screen for cognitive impairment and dementia after stroke and whether or not the MMSE can predict further deterioration or recovery in cognitive function over time. To this end, we studied 194 first-ever stroke patients without pre-stroke cognitive deterioration who underwent MMSEs and neuropsychological test batteries at 1, 6, 12, and 24 months after stroke. The MMSE score 1 month after stroke predicted cognitive functioning at later follow-up visits. It could not predict deterioration or improvement in cognitive functioning over time. The cut-off score in the screening for 1 cognitive disturbed domain was 27/28 with a sensitivity of 0.72. The cut-off score in the screening for at least 4 impaired domains and dementia were 26/27 and 23/24 with a sensitivity of 0.82 and 0.96, respectively. The results indicated that the MMSE has modest qualities in screening for mild cognitive disturbances and is adequate in screening for moderate cognitive deficits or dementia in stroke patients 1 month after stroke. Poor performance on the MMSE is predictive for cognitive impairment in the long term. However, it cannot be used to predict further cognitive deterioration or improvement over time. Springer-Verlag 2009-11-22 2010 /pmc/articles/PMC2848722/ /pubmed/20361295 http://dx.doi.org/10.1007/s00415-009-5387-9 Text en © The Author(s) 2009 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. |
spellingShingle | Original Communication Bour, Ariane Rasquin, Sascha Boreas, Anita Limburg, Martien Verhey, Frans How predictive is the MMSE for cognitive performance after stroke? |
title | How predictive is the MMSE for cognitive performance after stroke? |
title_full | How predictive is the MMSE for cognitive performance after stroke? |
title_fullStr | How predictive is the MMSE for cognitive performance after stroke? |
title_full_unstemmed | How predictive is the MMSE for cognitive performance after stroke? |
title_short | How predictive is the MMSE for cognitive performance after stroke? |
title_sort | how predictive is the mmse for cognitive performance after stroke? |
topic | Original Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848722/ https://www.ncbi.nlm.nih.gov/pubmed/20361295 http://dx.doi.org/10.1007/s00415-009-5387-9 |
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