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Tryptophan Scanning Analysis of the Membrane Domain of CTR-Copper Transporters
Membrane proteins of the CTR family mediate cellular copper uptake in all eukaryotic cells and have been shown to participate in uptake of platinum-based anticancer drugs. Despite their importance for life and the clinical treatment of malignancies, directed biochemical studies of CTR proteins have...
Autores principales: | De Feo, Christopher J., Mootien, Sara, Unger, Vinzenz M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848729/ https://www.ncbi.nlm.nih.gov/pubmed/20224886 http://dx.doi.org/10.1007/s00232-010-9239-4 |
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