Cargando…

ERK1/2 Signaling Dominates Over RhoA Signaling in Regulating Early Changes in RNA Expression Induced by Endothelin-1 in Neonatal Rat Cardiomyocytes

BACKGROUND: Cardiomyocyte hypertrophy is associated with changes in gene expression. Extracellular signal-regulated kinases 1/2 (ERK1/2) and RhoA [activated by hypertrophic agonists (e.g. endothelin-1)] regulate gene expression and are implicated in the response, but their relative significance in r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marshall, Andrew K., Barrett, Oliver P. T., Cullingford, Timothy E., Shanmugasundram, Achchuthan, Sugden, Peter H., Clerk, Angela
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848868/ https://www.ncbi.nlm.nih.gov/pubmed/20368814 http://dx.doi.org/10.1371/journal.pone.0010027

Ejemplares similares

Regulation of the cardiomyocyte transcriptome vs translatome by endothelin-1 and insulin: translational regulation of 5' terminal oligopyrimidine tract (TOP) mRNAs by insulin
por: Markou, Thomais, et al.
Publicado: (2010)

Differential regulation of Krüppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: Effects of endothelin-1, oxidative stress and cytokines
por: Cullingford, Timothy E., et al.
Publicado: (2008)

Temporal regulation of expression of immediate early and second phase transcripts by endothelin-1 in cardiomyocytes
por: Cullingford, Timothy E, et al.
Publicado: (2008)

Feedback regulation by Atf3 in the endothelin-1-responsive transcriptome of cardiomyocytes: Egr1 is a principal Atf3 target
por: Giraldo, Alejandro, et al.
Publicado: (2012)

RhoA Regulation of Cardiomyocyte Differentiation
por: Kaarbø, Mari, et al.
Publicado: (2013)

ERK-Smurf1-RhoA signaling is critical for TGFβ-drived EMT and tumor metastasis
por: Zheng, Jianzhong, et al.
Publicado: (2022)

Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling
por: Zhang, Jason Z., et al.
Publicado: (2020)

RhoA Signaling in Neurodegenerative Diseases
por: Schmidt, Sissel Ida, et al.
Publicado: (2022)

p90 Ribosomal S6 kinases play a significant role in early gene regulation in the cardiomyocyte response to G(q)-protein-coupled receptor stimuli, endothelin-1 and α(1)-adrenergic receptor agonists
por: Amirak, Emre, et al.
Publicado: (2013)

Interplay of cell–cell contacts and RhoA/MRTF‐A signaling regulates cardiomyocyte identity
por: Dorn, Tatjana, et al.
Publicado: (2018)

Stimulation of the p38 Mitogen-activated Protein Kinase Pathway in Neonatal Rat Ventricular Myocytes by the G Protein–coupled Receptor Agonists, Endothelin-1 and Phenylephrine: A Role in Cardiac Myocyte Hypertrophy?
por: Clerk, Angela, et al.
Publicado: (1998)

RhoA-ROCK signaling is involved in contraction-mediated inhibition of SERCA2a expression in cardiomyocytes
por: Vlasblom, Ronald, et al.
Publicado: (2009)

RhoA signaling increases mitophagy and protects cardiomyocytes against ischemia by stabilizing PINK1 protein and recruiting Parkin to mitochondria
por: Tu, Michelle, et al.
Publicado: (2022)

Herbal Prescription, DSGOST, Prevents Cold-Induced RhoA Activation and Endothelin-1 Production in Endothelial Cells
por: Cho, Sung-Gook, et al.
Publicado: (2014)

RhoA/Rho-kinase signaling: a therapeutic target in pulmonary hypertension
por: Barman, Scott A, et al.
Publicado: (2009)

Discoidin domain receptor 1 promotes Th17 cell migration by activating the RhoA/ROCK/MAPK/ERK signaling pathway
por: Azreq, Mohammed-Amine El, et al.
Publicado: (2016)

KMUP-1 Attenuates Endothelin-1-Induced Cardiomyocyte Hypertrophy through Activation of Heme Oxygenase-1 and Suppression of the Akt/GSK-3β, Calcineurin/NFATc4 and RhoA/ROCK Pathways
por: Liou, Shu-Fen, et al.
Publicado: (2015)

Inhibition of β1-AR/Gαs signaling promotes cardiomyocyte proliferation in juvenile mice through activation of RhoA-YAP axis
por: Sakabe, Masahide, et al.
Publicado: (2022)

RhoA Signaling in Immune Cell Response and Cardiac Disease
por: Kilian, Lucia Sophie, et al.
Publicado: (2021)

Dysbindin is a potent inducer of RhoA–SRF-mediated cardiomyocyte hypertrophy
por: Rangrez, Ashraf Yusuf, et al.
Publicado: (2013)

Monophosphothreonyl extracellular signal-regulated kinases 1 and 2 (ERK1/2) are formed endogenously in intact cardiac myocytes and are enzymically active
por: Sugden, Peter H., et al.
Publicado: (2011)

Endothelin-1 Upregulates Activin Receptor-Like Kinase-1 Expression via Gi/RhoA/Sp-1/Rho Kinase Pathways in Human Pulmonary Arterial Endothelial Cells
por: Sugimoto, Koichi, et al.
Publicado: (2021)

Cholecystokinin-Mediated RhoGDI Phosphorylation via PKCα Promotes both RhoA and Rac1 Signaling
por: Sabbatini, Maria Eugenia, et al.
Publicado: (2013)

Corrigendum to “Monophosphothreonyl extracellular signal-regulated kinases 1 and 2 (ERK1/2) are formed endogenously in intact cardiac myocytes and are enzymically active” [Cell Signal 23 (2011) 468–477]
por: Sugden, Peter H., et al.
Publicado: (2011)

Phosphorylation and Activation of RhoA by ERK in Response to Epidermal Growth Factor Stimulation
por: Tong, Junfeng, et al.
Publicado: (2016)

Matrix-Bound PAI-1 Supports Cell Blebbing via RhoA/ROCK1 Signaling
por: Cartier-Michaud, Amandine, et al.
Publicado: (2012)

Rap1 organizes lymphocyte front-back polarity via RhoA signaling and talin1
por: Ueda, Yoshihiro, et al.
Publicado: (2023)

The Small GTPase RhoA Localizes to the Nucleus and Is Activated by Net1 and DNA Damage Signals
por: Dubash, Adi D., et al.
Publicado: (2011)

Polycystin-1 regulates ARHGAP35-dependent centrosomal RhoA activation and ROCK signaling
por: Streets, Andrew J., et al.
Publicado: (2020)

RhoA/ROCK-1 Signaling Pathway and Oxidative Stress in Coronary Artery Disease Patients
por: Dokumacioglu, Eda, et al.
Publicado: (2022)

Mechanism of RhoA regulating benign prostatic hyperplasia: RhoA-ROCK-β-catenin signaling axis and static & dynamic dual roles
por: Shan, Shidong, et al.
Publicado: (2023)

NKCC1 promotes EMT‐like process in GBM via RhoA and Rac1 signaling pathways
por: Ma, Haiwen, et al.
Publicado: (2018)

RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling
por: Wang, Fan, et al.
Publicado: (2017)

Cardiomyocyte BRAF is a key signalling intermediate in cardiac hypertrophy in mice
por: Alharbi, Hajed O., et al.
Publicado: (2022)

Differential ERK1/2 Signaling and Hypertrophic Response to Endothelin-1 in Cardiomyocytes from SHR and Wistar-Kyoto Rats: A Potential Target for Combination Therapy of Hypertension
por: Zhu, Li-an, et al.
Publicado: (2015)

RhoA improves cryopreservation of rooster sperm through the Rho/RhoA-associated kinase/cofilin pathway
por: Heng, Nuo, et al.
Publicado: (2022)

Negative regulation of RhoA translation and signaling by hnRNP-Q1 affects cellular morphogenesis
por: Xing, Lei, et al.
Publicado: (2012)

RhoA/ROCK Signaling and Pleiotropic α(1A)-Adrenergic Receptor Regulation of Cardiac Contractility
por: Yu, Ze-Yan, et al.
Publicado: (2014)

The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1
por: Dubash, Adi D., et al.
Publicado: (2013)

Sphingosine 1-phosphate receptor 3 and RhoA signaling mediate inflammatory gene expression in astrocytes
por: Dusaban, Stephanie S., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_as0ptv38gofknjoek909400fam