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Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation

BACKGROUND: Numerous studies have demonstrated associations between genetic markers and COPD, but results have been inconsistent. One reason may be heterogeneity in disease definition. Unsupervised learning approaches may assist in understanding disease heterogeneity. METHODS: We selected 31 phenoty...

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Detalles Bibliográficos
Autores principales: Cho, Michael H, Washko, George R, Hoffmann, Thomas J, Criner, Gerard J, Hoffman, Eric A, Martinez, Fernando J, Laird, Nan, Reilly, John J, Silverman, Edwin K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850331/
https://www.ncbi.nlm.nih.gov/pubmed/20233420
http://dx.doi.org/10.1186/1465-9921-11-30