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Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation
BACKGROUND: Numerous studies have demonstrated associations between genetic markers and COPD, but results have been inconsistent. One reason may be heterogeneity in disease definition. Unsupervised learning approaches may assist in understanding disease heterogeneity. METHODS: We selected 31 phenoty...
Autores principales: | Cho, Michael H, Washko, George R, Hoffmann, Thomas J, Criner, Gerard J, Hoffman, Eric A, Martinez, Fernando J, Laird, Nan, Reilly, John J, Silverman, Edwin K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850331/ https://www.ncbi.nlm.nih.gov/pubmed/20233420 http://dx.doi.org/10.1186/1465-9921-11-30 |
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