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Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments

BACKGROUND: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor and a similar structure; pairwise sequence alignments often fail to represent accurately the structural alignments inferr...

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Detalles Bibliográficos
Autores principales: Sierk, Michael L, Smoot, Michael E, Bass, Ellen J, Pearson, William R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850363/
https://www.ncbi.nlm.nih.gov/pubmed/20307279
http://dx.doi.org/10.1186/1471-2105-11-146