Bicaudal D2, Dynein, and Kinesin-1 Associate with Nuclear Pore Complexes and Regulate Centrosome and Nuclear Positioning during Mitotic Entry

BICD2 is one of the two mammalian homologues of the Drosophila Bicaudal D, an evolutionarily conserved adaptor between microtubule motors and their cargo that was previously shown to link vesicles and mRNP complexes to the dynein motor. Here, we identified a G2-specific role for BICD2 in the relativ...

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Detalles Bibliográficos
Autores principales: Splinter, Daniël, Tanenbaum, Marvin E., Lindqvist, Arne, Jaarsma, Dick, Flotho, Annette, Yu, Ka Lou, Grigoriev, Ilya, Engelsma, Dieuwke, Haasdijk, Elize D., Keijzer, Nanda, Demmers, Jeroen, Fornerod, Maarten, Melchior, Frauke, Hoogenraad, Casper C., Medema, René H., Akhmanova, Anna
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850381/
https://www.ncbi.nlm.nih.gov/pubmed/20386726
http://dx.doi.org/10.1371/journal.pbio.1000350

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