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Could recombinant insulin compounds contribute to adenocarcinoma progression by stimulating local angiogenesis?

AIMS/HYPOTHESIS: Negative effects on the progression of adenocarcinomas by hyperinsulinaemia and the insulin analogue glargine (A21Gly,B31Arg,B32Arg human insulin) have recently been suggested. Most actions of this insulin analogue have hitherto been explained by direct stimulation of growth potenti...

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Detalles Bibliográficos
Autores principales: Rensing, K. L., Houttuijn Bloemendaal, F. M., Weijers, E. M., Richel, D. J., Büller, H. R., Koolwijk, P., van der Loos, C. M., Twickler, Th. B., von der Thüsen, J. H.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850513/
https://www.ncbi.nlm.nih.gov/pubmed/20182859
http://dx.doi.org/10.1007/s00125-010-1687-y