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CyDNA: Synthesis and Replication of Highly Cy-Dye Substituted DNA by an Evolved Polymerase
[Image: see text] DNA not only transmits genetic information but can also serve as a versatile supramolecular scaffold. Here we describe a strategy for the synthesis and replication of DNA displaying hundreds of substituents using directed evolution of polymerase function by short-patch compartmenta...
Autores principales: | Ramsay, Nicola, Jemth, Ann-Sofie, Brown, Anthony, Crampton, Neal, Dear, Paul, Holliger, Philipp |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850551/ https://www.ncbi.nlm.nih.gov/pubmed/20235594 http://dx.doi.org/10.1021/ja909180c |
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