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Functional Differences between the N-Terminal Domains of Mouse and Human Myosin Binding Protein-C

The N-terminus of cMyBP-C can activate actomyosin interactions in the absence of Ca(2+), but it is unclear which domains are necessary. Prior studies suggested that the Pro-Ala rich region of human cMyBP-C activated force in permeabilized human cardiomyocytes, whereas the C1 and M-domains of mouse c...

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Detalles Bibliográficos
Autores principales: Shaffer, Justin F., Wong, Peony, Bezold, Kristina L., Harris, Samantha P.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850553/
https://www.ncbi.nlm.nih.gov/pubmed/20379391
http://dx.doi.org/10.1155/2010/789798