Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease

DNA polymorphisms in a region on chromosome 5q33.1 which contains two genes, immunity related GTPase related family, M (IRGM) and zinc finger protein 300 (ZNF300), are associated with Crohn's disease (CD). The deleted allele of a 20 kb copy number variation (CNV) upstream of IRGM was recently s...

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Detalles Bibliográficos
Autores principales: Prescott, Natalie J., Dominy, Katherine M., Kubo, Michiaki, Lewis, Cathryn M., Fisher, Sheila A., Redon, Richard, Huang, Ni, Stranger, Barbara E., Blaszczyk, Katarzyna, Hudspith, Barry, Parkes, Gareth, Hosono, Naoya, Yamazaki, Keiko, Onnie, Clive M., Forbes, Alastair, Dermitzakis, Emmanouil T., Nakamura, Yusuke, Mansfield, John C., Sanderson, Jeremy, Hurles, Matthew E., Roberts, Roland G., Mathew, Christopher G.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Association Studies Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850616/
https://www.ncbi.nlm.nih.gov/pubmed/20106866
http://dx.doi.org/10.1093/hmg/ddq041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850616/
https://www.ncbi.nlm.nih.gov/pubmed/20106866
http://dx.doi.org/10.1093/hmg/ddq041

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