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Toxoplasma secreting Cre recombinase for analysis of host-parasite interactions

We describe the use of site specific recombination to study the host-parasite interactions of Toxoplasma gondii. We present a Toxoplasma strain that efficiently injects a Cre fusion protein into host cells. In a Cre-reporter cell line, a single parasite invasion induced Cre-mediated recombination in...

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Detalles Bibliográficos
Autores principales: Koshy, Anita A., Fouts, Ashley E., Lodoen, Melissa B., Alkan, Ozan, Blau, Helen M., Boothroyd, John C.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850821/
https://www.ncbi.nlm.nih.gov/pubmed/20208532
http://dx.doi.org/10.1038/nmeth.1438