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Epidermal growth factor receptor regulates β-catenin location, stability, and transcriptional activity in oral cancer
BACKGROUND: Many cancerous cells accumulate β-catenin in the nucleus. We examined the role of epidermal growth factor receptor (EGFR) signaling in the accumulation of β-catenin in the nuclei of oral cancer cells. RESULTS: We used two strains of cultured oral cancer cells, one with reduced EGFR expre...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850885/ https://www.ncbi.nlm.nih.gov/pubmed/20302655 http://dx.doi.org/10.1186/1476-4598-9-64 |