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Epidermal growth factor receptor regulates β-catenin location, stability, and transcriptional activity in oral cancer

BACKGROUND: Many cancerous cells accumulate β-catenin in the nucleus. We examined the role of epidermal growth factor receptor (EGFR) signaling in the accumulation of β-catenin in the nuclei of oral cancer cells. RESULTS: We used two strains of cultured oral cancer cells, one with reduced EGFR expre...

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Detalles Bibliográficos
Autores principales:	Lee, Chien-Hsing, Hung, Hsing-Wen, Hung, Pei-Hsin, Shieh, Yi-Shing
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850885/ https://www.ncbi.nlm.nih.gov/pubmed/20302655 http://dx.doi.org/10.1186/1476-4598-9-64

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