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Efficient inhibition of hepatitis B virus replication by hepatitis delta virus ribozymes delivered by targeting retrovirus

BACKGROUND: Hepatitis delta virus (HDV) ribozyme is an attractive molecular tool that can specifically recognize and catalyze the self-cleavage of the viral RNA phosphodiester backbone. However, a major obstacle in the medical application of the HDV ribozyme is the lack of specificity in the deliver...

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Detalles Bibliográficos
Autores principales: Wang, Chuan-Xi, Lu, Yan-Qin, Qi, Peng, Chen, Long-Hua, Han, Jin-Xiang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850903/
https://www.ncbi.nlm.nih.gov/pubmed/20236514
http://dx.doi.org/10.1186/1743-422X-7-61