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A System-Wide Investigation of the Dynamics of Wnt Signaling Reveals Novel Phases of Transcriptional Regulation

Aberrant Wnt signaling has been implicated in a wide variety of cancers and many components of the Wnt signaling network have now been identified. Much less is known, however, about how these proteins are coordinately regulated. Here, a broad, quantitative, and dynamic study of Wnt3a-mediated stimul...

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Detalles Bibliográficos
Autores principales: Gujral, Taranjit S., MacBeath, Gavin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850918/
https://www.ncbi.nlm.nih.gov/pubmed/20383323
http://dx.doi.org/10.1371/journal.pone.0010024