Unexpected death from a colloid cyst

BACKGROUND: Colloid cysts are usually benign brain tumors, which rarely cause acute neurological deterioration with sudden death due to an acute increase of intracranial pressure. So far, the final pathophysiology and clinical signs of impending death are unclear in this context. AIM: We present a case of an adolescent who presented with symptoms similar to gastroenteritis. RESULTS: He unexpectedly developed a generalized seizure, acute pulmonary edema and life-threatening cardiac dysrhythmia. CONCLUSION: Subtle distinctions between symptoms due to intracranial hypertension, which typically cause headache and vomiting, and true gastroenteritis are discussed as well as the pathophysiology of neurogenic pulmonary edema and the origin of cerebral-triggered cardiac dysrhythmias. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s12245-009-0153-4) contains supplementary material, which is available to authorized users.