Predominance of Rotavirus P[4]G2 in a Vaccinated Population, Brazil

We identified 21 rotaviruses in 129 patients with diarrhea in a Brazilian city with high rotavirus vaccine coverage. All rotaviruses were genotype P[4]G2 with 1 mixed infection with P[NT]G9. Although virus predominance could have occurred randomly, the vaccine may be less protective against P[4]G2....

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Detalles Bibliográficos
Autores principales: Gurgel, Ricardo Q., Cuevas, Luis E., Vieira, Sarah C.F., Barros, Vanessa C.F., Fontes, Paula B., Salustino, Eduardo F., Nakagomi, Osamu, Nakagomi, Toyoko, Dove, Winifred, Cunliffe, Nigel, Hart, Charles A.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2007
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851506/
https://www.ncbi.nlm.nih.gov/pubmed/18258011
http://dx.doi.org/10.3201/eid1310.070412
Descripción
Sumario:We identified 21 rotaviruses in 129 patients with diarrhea in a Brazilian city with high rotavirus vaccine coverage. All rotaviruses were genotype P[4]G2 with 1 mixed infection with P[NT]G9. Although virus predominance could have occurred randomly, the vaccine may be less protective against P[4]G2. Prospective surveillance is urgently needed.

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