Cargando…

Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression

Single nucleotide polymorphisms (SNPs) on chromosome 9p21 are associated with coronary artery disease, diabetes, and multiple cancers. Risk SNPs are mainly non-coding, suggesting that they influence expression and may act in cis. We examined the association between 56 SNPs in this region and periphe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cunnington, Michael S., Santibanez Koref, Mauro, Mayosi, Bongani M., Burn, John, Keavney, Bernard
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851566/ https://www.ncbi.nlm.nih.gov/pubmed/20386740 http://dx.doi.org/10.1371/journal.pgen.1000899

Ejemplares similares

Chromosome 16q22 variants in a region associated with cardiovascular phenotypes correlate with ZFHX3 expression in a transcript-specific manner
por: Martin, Ruairidh I R, et al.
Publicado: (2014)

STK39 polymorphisms and blood pressure: an association study in British Caucasians and assessment of cis-acting influences on gene expression
por: Cunnington, Michael S, et al.
Publicado: (2009)

Methylation of p15(INK4b) and Expression of ANRIL on Chromosome 9p21 Are Associated with Coronary Artery Disease
por: Zhuang, Jianhui, et al.
Publicado: (2012)

Long Noncoding RNA ANRIL: Lnc-ing Genetic Variation at the Chromosome 9p21 Locus to Molecular Mechanisms of Atherosclerosis
por: Holdt, Lesca M., et al.
Publicado: (2018)

Association of stroke and bleed events in non-valvular atrial fibrillation patients with direct oral anticoagulant prescriptions in NHS England between 2013 and 2016
por: Sheth, Harsh, et al.
Publicado: (2019)

Relationship between CAD Risk Genotype in the Chromosome 9p21 Locus and Gene Expression. Identification of Eight New ANRIL Splice Variants
por: Folkersen, Lasse, et al.
Publicado: (2009)

Atrial fibrillation associated with ivabradine treatment: meta-analysis of randomised controlled trials
por: Martin, Ruairidh I R, et al.
Publicado: (2014)

Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate Atherogenic Cell Functions through Trans-Regulation of Gene Networks
por: Holdt, Lesca M., et al.
Publicado: (2013)

Allelic Imbalance in Regulation of ANRIL through Chromatin Interaction at 9p21 Endometriosis Risk Locus
por: Nakaoka, Hirofumi, et al.
Publicado: (2016)

Phenotype-specific effect of chromosome 1q21.1 rearrangements and GJA5 duplications in 2436 congenital heart disease patients and 6760 controls
por: Soemedi, Rachel, et al.
Publicado: (2012)

Novel genetic variants linked to coronary artery disease by genome-wide association are not associated with carotid artery intima-media thickness or intermediate risk phenotypes
por: Cunnington, M.S., et al.
Publicado: (2009)

Using population data for assessing next-generation sequencing performance
por: Houniet, Darren T., et al.
Publicado: (2015)

Increased expression of fatty acid binding protein 4 and leptin in resident macrophages characterises atherosclerotic plaque rupture
por: Lee, K., et al.
Publicado: (2013)

The Role of ANRIL in Atherosclerosis
por: Razeghian-Jahromi, Iman, et al.
Publicado: (2022)

Roles of the Chr.9p21.3 ANRIL Locus in Regulating Inflammation and Implications for Anti-Inflammatory Drug Target Identification
por: Aarabi, Ghazal, et al.
Publicado: (2018)

ANRIL regulates multiple molecules of pathogenetic significance in diabetic nephropathy
por: Sooshtari, Parisa, et al.
Publicado: (2022)

Common Variation Neighbouring Micro-RNA 22 Is Associated with Increased Left Ventricular Mass
por: Harper, Andrew R., et al.
Publicado: (2013)

Genetic Variation at Selected SNPs in the Leptin Gene and Association of Alleles with Markers of Kidney Disease in a Xhosa Population of South Africa
por: Okpechi, Ikechi G., et al.
Publicado: (2010)

Cardiomyopathies and myocardial disorders in Africa: present status and the way forward
por: Mayosi, Bongani M
Publicado: (2013)

Variants in ANRIL gene correlated with its expression contribute to myocardial infarction risk
por: Cheng, Jie, et al.
Publicado: (2017)

Sebaceous tumours: a prototypical class of skin tumour for universal germline genetic testing
por: Gallon, R., et al.
Publicado: (2021)

How Should We Test for Lynch Syndrome? A Review of Current Guidelines and Future Strategies
por: Gallon, Richard, et al.
Publicado: (2021)

Multiple Isoforms of ANRIL in Melanoma Cells: Structural Complexity Suggests Variations in Processing
por: Sarkar, Debina, et al.
Publicado: (2017)

DNA methylation at birth within the promoter of ANRIL predicts markers of cardiovascular risk at 9 years
por: Murray, Robert, et al.
Publicado: (2016)

ANRIL: Molecular Mechanisms and Implications in Human Health
por: Congrains, Ada, et al.
Publicado: (2013)

The Long Non-Coding RNA ANRIL in Cancers
por: Sanchez, Aymeric, et al.
Publicado: (2023)

Human Chondrocytes Respond Discordantly to the Protein Encoded by the Osteoarthritis Susceptibility Gene GDF5
por: Ratnayake, Madhushika, et al.
Publicado: (2014)

Circulating cell-free mitochondrial DNA levels in Parkinson’s disease are influenced by treatment
por: Lowes, Hannah, et al.
Publicado: (2020)

Mapping Insertions, Deletions and SNPs on Venter's Chromosomes
por: Costantini, Maria, et al.
Publicado: (2009)

Genomic medicine in Africa: promise, problems and prospects
por: Wonkam, Ambroise, et al.
Publicado: (2014)

Cardiomyopathy in Africa: heredity versus environment
por: Mayosi, Bongani M, et al.
Publicado: (2007)

The Pan-African Society of Cardiology (PASCAR) in 2013 and beyond
por: Dzudie, Anastase, et al.
Publicado: (2013)

Impact of Molecular Genetics on Clinical Cardiology
por: Mayosi, Bongani M, et al.
Publicado: (1999)

Genotype at the P554L Variant of the Hexose-6 Phosphate Dehydrogenase Gene Is Associated with Carotid Intima-Medial Thickness
por: Rahman, Thahira J., et al.
Publicado: (2011)

Diagnostic value of circulating lncRNA ANRIL and its correlation with coronary artery disease parameters
por: Hu, Yao, et al.
Publicado: (2019)

Serum lncRNA-ANRIL and SOX9 expression levels in glioma patients and their relationship with poor prognosis
por: Sun, Youlu, et al.
Publicado: (2021)

Functional Characterization of the Osteoarthritis Susceptibility Mapping to CHST11—A Bioinformatics and Molecular Study
por: Reynard, Louise N., et al.
Publicado: (2016)

ANRIL Genetic Variants in Iranian Breast Cancer Patients
por: Khorshidi, Hamid Reza, et al.
Publicado: (2017)

Allelic imbalance of chromosome 6q in ovarian tumours.
por: Orphanos, V., et al.
Publicado: (1995)

The role of the RAS pathway in iAMP21-ALL
por: Ryan, S L, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_h1b3osnd30a8pef470t3t1jam3