Distinct Roles of Hand2 in Initiating Polarity and Posterior Shh Expression during the Onset of Mouse Limb Bud Development

The polarization of nascent embryonic fields and the endowment of cells with organizer properties are key to initiation of vertebrate organogenesis. One such event is antero-posterior (AP) polarization of early limb buds and activation of morphogenetic Sonic Hedgehog (SHH) signaling in the posterior...

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Detalles Bibliográficos
Autores principales: Galli, Antonella, Robay, Dimitri, Osterwalder, Marco, Bao, Xiaozhong, Bénazet, Jean-Denis, Tariq, Muhammad, Paro, Renato, Mackem, Susan, Zeller, Rolf
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851570/
https://www.ncbi.nlm.nih.gov/pubmed/20386744
http://dx.doi.org/10.1371/journal.pgen.1000901

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