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Variants of the Matrix Metalloproteinase-2 but not the Matrix Metalloproteinase-9 genes significantly influence functional outcome after stroke

BACKGROUND: Multiple lines of evidence suggest that genetic factors contribute to stroke recovery. The matrix metalloproteinases -2 (MMP-2) and -9 (MMP-9) are modulators of extracellular matrix components, with important regulatory functions in the Central Nervous System (CNS). Shortly after stroke,...

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Detalles Bibliográficos
Autores principales: Manso, Helena, Krug, Tiago, Sobral, João, Albergaria, Isabel, Gaspar, Gisela, Ferro, José M, Oliveira, Sofia A, Vicente, Astrid M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851591/
https://www.ncbi.nlm.nih.gov/pubmed/20222942
http://dx.doi.org/10.1186/1471-2350-11-40