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α-Synuclein overexpression increases dopamine toxicity in BE(2)-M17 cells
BACKGROUND: Oxidative stress has been proposed to be involved in the pathogenesis of Parkinson's disease (PD). A plausible source of oxidative stress in nigral dopaminergic neurons is the redox reactions that specifically involve dopamine and produce various toxic molecules, i.e., free radicals...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851596/ https://www.ncbi.nlm.nih.gov/pubmed/20334701 http://dx.doi.org/10.1186/1471-2202-11-41 |