A Mycobacterium tuberculosis Sigma Factor Network Responds to Cell-Envelope Damage by the Promising Anti-Mycobacterial Thioridazine

BACKGROUND: Novel therapeutics are urgently needed to control tuberculosis (TB). Thioridazine (THZ) is a candidate for the therapy of multidrug and extensively drug-resistant TB. METHODOLOGY/PRINCIPAL FINDINGS: We studied the impact of THZ on Mycobacterium tuberculosis (Mtb) by analyzing gene expres...

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Detalles Bibliográficos
Autores principales: Dutta, Noton K., Mehra, Smriti, Kaushal, Deepak
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851646/
https://www.ncbi.nlm.nih.gov/pubmed/20386700
http://dx.doi.org/10.1371/journal.pone.0010069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851646/
https://www.ncbi.nlm.nih.gov/pubmed/20386700
http://dx.doi.org/10.1371/journal.pone.0010069

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