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Exposure to HIV-1 Directly Impairs Mucosal Epithelial Barrier Integrity Allowing Microbial Translocation
While several clinical studies have shown that HIV-1 infection is associated with increased permeability of the intestinal tract, there is very little understanding of the mechanisms underlying HIV-induced impairment of mucosal barriers. Here we demonstrate that exposure to HIV-1 can directly breach...
Autores principales: | Nazli, Aisha, Chan, Olivia, Dobson-Belaire, Wendy N., Ouellet, Michel, Tremblay, Michel J., Gray-Owen, Scott D., Arsenault, A. Larry, Kaushic, Charu |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851733/ https://www.ncbi.nlm.nih.gov/pubmed/20386714 http://dx.doi.org/10.1371/journal.ppat.1000852 |
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