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The Mycobacterium tuberculosis gene, ldt(Mt2), encodes a non-classical transpeptidase required for virulence and resistance to amoxicillin
The peptidoglycan layer is a vital component of the bacterial cell wall. The existing paradigm describes the peptidoglycan network as a static structure that is cross-linked predominantly by 4→3 transpeptide linkages. However, the non-classical 3→3 linkages predominate the transpeptide networking of...
Autores principales: | Gupta, Radhika, Lavollay, Marie, Mainardi, Jean-Luc, Arthur, Michel, Bishai, William R., Lamichhane, Gyanu |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851841/ https://www.ncbi.nlm.nih.gov/pubmed/20305661 http://dx.doi.org/10.1038/nm.2120 |
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