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Enhancing DNA vaccine potency by co-administration of xenogenic MHC-class-I DNA
Intramuscular administration of DNA vaccines can lead to the generation of antigen-specific immune responses through cross-priming mechanisms. We propose a strategy that is capable of leading to local inflammation and enhancing cross-priming, thus resulting in improved antigen-specific immune respon...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851845/ https://www.ncbi.nlm.nih.gov/pubmed/19940864 http://dx.doi.org/10.1038/gt.2009.152 |