Physicochemical and Pharmacokinetic Parameters in Drug Selection and Loading for Transdermal Drug Delivery

Skin of an average adult body covers a surface of approximately 2 m2 and receives about one-third of the blood circulating through the body. The transdermal route of administration cannot be employed for a large number of drugs. The rationality of drug selection based on pharmacokinetic parameters a...

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Detalles Bibliográficos
Autores principales: Chandrashekar, N. S., Shobha Rani, R. H.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2008
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852070/
https://www.ncbi.nlm.nih.gov/pubmed/20390089
http://dx.doi.org/10.4103/0250-474X.40340
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author Chandrashekar, N. S.
Shobha Rani, R. H.
author_facet Chandrashekar, N. S.
Shobha Rani, R. H.
author_sort Chandrashekar, N. S.
collection PubMed
description Skin of an average adult body covers a surface of approximately 2 m2 and receives about one-third of the blood circulating through the body. The transdermal route of administration cannot be employed for a large number of drugs. The rationality of drug selection based on pharmacokinetic parameters and physicochemical properties of the drug are the important factors to be considered for deciding its suitability of drug for delivery by transdermal route.
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spelling pubmed-28520702010-04-13 Physicochemical and Pharmacokinetic Parameters in Drug Selection and Loading for Transdermal Drug Delivery Chandrashekar, N. S. Shobha Rani, R. H. Indian J Pharm Sci Short Communication Skin of an average adult body covers a surface of approximately 2 m2 and receives about one-third of the blood circulating through the body. The transdermal route of administration cannot be employed for a large number of drugs. The rationality of drug selection based on pharmacokinetic parameters and physicochemical properties of the drug are the important factors to be considered for deciding its suitability of drug for delivery by transdermal route. Medknow Publications 2008 /pmc/articles/PMC2852070/ /pubmed/20390089 http://dx.doi.org/10.4103/0250-474X.40340 Text en © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Chandrashekar, N. S.
Shobha Rani, R. H.
Physicochemical and Pharmacokinetic Parameters in Drug Selection and Loading for Transdermal Drug Delivery
title Physicochemical and Pharmacokinetic Parameters in Drug Selection and Loading for Transdermal Drug Delivery
title_full Physicochemical and Pharmacokinetic Parameters in Drug Selection and Loading for Transdermal Drug Delivery
title_fullStr Physicochemical and Pharmacokinetic Parameters in Drug Selection and Loading for Transdermal Drug Delivery
title_full_unstemmed Physicochemical and Pharmacokinetic Parameters in Drug Selection and Loading for Transdermal Drug Delivery
title_short Physicochemical and Pharmacokinetic Parameters in Drug Selection and Loading for Transdermal Drug Delivery
title_sort physicochemical and pharmacokinetic parameters in drug selection and loading for transdermal drug delivery
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852070/
https://www.ncbi.nlm.nih.gov/pubmed/20390089
http://dx.doi.org/10.4103/0250-474X.40340
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AT shobharanirh physicochemicalandpharmacokineticparametersindrugselectionandloadingfortransdermaldrugdelivery

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