Optimization of data collection taking radiation damage into account

To take into account the effects of radiation damage, new algorithms for the optimization of data-collection strategies have been implemented in the software package BEST. The intensity variation related to radiation damage is approximated by log-linear functions of resolution and cumulative X-­ray...

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Detalles Bibliográficos
Autores principales: Bourenkov, Gleb P., Popov, Alexander N.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852305/
https://www.ncbi.nlm.nih.gov/pubmed/20382994
http://dx.doi.org/10.1107/S0907444909054961
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author Bourenkov, Gleb P.
Popov, Alexander N.
author_facet Bourenkov, Gleb P.
Popov, Alexander N.
author_sort Bourenkov, Gleb P.
collection PubMed
description To take into account the effects of radiation damage, new algorithms for the optimization of data-collection strategies have been implemented in the software package BEST. The intensity variation related to radiation damage is approximated by log-linear functions of resolution and cumulative X-­ray dose. Based on an accurate prediction of the basic characteristics of data yet to be collected, BEST establishes objective relationships between the accessible data completeness, resolution and signal-to-noise statistics that can be achieved in an experiment and designs an optimal plan for data collection.
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spelling pubmed-28523052010-04-13 Optimization of data collection taking radiation damage into account Bourenkov, Gleb P. Popov, Alexander N. Acta Crystallogr D Biol Crystallogr Research Papers To take into account the effects of radiation damage, new algorithms for the optimization of data-collection strategies have been implemented in the software package BEST. The intensity variation related to radiation damage is approximated by log-linear functions of resolution and cumulative X-­ray dose. Based on an accurate prediction of the basic characteristics of data yet to be collected, BEST establishes objective relationships between the accessible data completeness, resolution and signal-to-noise statistics that can be achieved in an experiment and designs an optimal plan for data collection. International Union of Crystallography 2010-04-01 2010-03-24 /pmc/articles/PMC2852305/ /pubmed/20382994 http://dx.doi.org/10.1107/S0907444909054961 Text en © Bourenkov & Popov 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Research Papers
Bourenkov, Gleb P.
Popov, Alexander N.
Optimization of data collection taking radiation damage into account
title Optimization of data collection taking radiation damage into account
title_full Optimization of data collection taking radiation damage into account
title_fullStr Optimization of data collection taking radiation damage into account
title_full_unstemmed Optimization of data collection taking radiation damage into account
title_short Optimization of data collection taking radiation damage into account
title_sort optimization of data collection taking radiation damage into account
topic Research Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852305/
https://www.ncbi.nlm.nih.gov/pubmed/20382994
http://dx.doi.org/10.1107/S0907444909054961
work_keys_str_mv AT bourenkovglebp optimizationofdatacollectiontakingradiationdamageintoaccount
AT popovalexandern optimizationofdatacollectiontakingradiationdamageintoaccount

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