Inhibition of the Proprotein Convertases Represses the Invasiveness of Human Primary Melanoma Cells with Altered p53, CDKN2A and N-Ras Genes

BACKGROUND: Altered tumor suppressor p53 and/or CDKN2A as well as Ras genes are frequently found in primary and metastatic melanomas. These alterations were found to be responsible for acquisition of invasive and metastatic potential through their defective regulatory control of metalloproteinases a...

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Detalles Bibliográficos
Autores principales: Lalou, Claude, Scamuffa, Nathalie, Mourah, Samia, Plassa, Francois, Podgorniak, Marie-Pierre, Soufir, Nadem, Dumaz, Nicolas, Calvo, Fabien, Basset-Seguin, Nicole, Khatib, Abdel-Majid
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852400/
https://www.ncbi.nlm.nih.gov/pubmed/20404912
http://dx.doi.org/10.1371/journal.pone.0009992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852400/
https://www.ncbi.nlm.nih.gov/pubmed/20404912
http://dx.doi.org/10.1371/journal.pone.0009992

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