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Shared Active Site Architecture between the Large Subunit of Eukaryotic Primase and DNA Photolyase
BACKGROUND: DNA synthesis during replication relies on RNA primers synthesised by the primase, a specialised DNA-dependent RNA polymerase that can initiate nucleic acid synthesis de novo. In archaeal and eukaryotic organisms, the primase is a heterodimeric enzyme resulting from the constitutive asso...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852410/ https://www.ncbi.nlm.nih.gov/pubmed/20404922 http://dx.doi.org/10.1371/journal.pone.0010083 |