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Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model
MicroRNAs (miRNAs) are increasingly implicated in regulating metastasis. Despite progress in silencing miRNAs in normal tissues of rodents and non-human primates, the development of effective approaches for sequence-specific inhibition of miRNAs in fast-growing tumors remains a significant scientifi...
Autores principales: | Ma, Li, Reinhardt, Ferenc, Pan, Elizabeth, Soutschek, Jürgen, Bhat, Balkrishen, Marcusson, Eric, Teruya-Feldstein, Julie, Bell, George W., Weinberg, Robert A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852471/ https://www.ncbi.nlm.nih.gov/pubmed/20351690 http://dx.doi.org/10.1038/nbt.1618 |
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