Percutaneous Liver Biopsy after Living Donor Liver Transplantation Resulting in Fulminant Hepatic Failure: The First Reported Case of Hepatic Compartment Syndrome

A 28-year-old female who underwent live donor liver transplantation 3 years prior presented after percutaneous liver biopsy with abdominal and shoulder pain, nausea, vomiting, and elevated liver enzymes. Computed tomography (CT) showed an intrahepatic and subcapsular hematoma. There was a progressiv...

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Autores principales: Nissen, Nicholas N., Geller, Stephen A., Klein, Andrew, Colquhoun, Steve, Yamini, David, Tran, Tram T., Weinberg, Benjamin, Winn, Julie, Poordad, Fred
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852596/
https://www.ncbi.nlm.nih.gov/pubmed/20396383
http://dx.doi.org/10.1155/2010/273578
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author Nissen, Nicholas N.
Geller, Stephen A.
Klein, Andrew
Colquhoun, Steve
Yamini, David
Tran, Tram T.
Weinberg, Benjamin
Winn, Julie
Poordad, Fred
author_facet Nissen, Nicholas N.
Geller, Stephen A.
Klein, Andrew
Colquhoun, Steve
Yamini, David
Tran, Tram T.
Weinberg, Benjamin
Winn, Julie
Poordad, Fred
author_sort Nissen, Nicholas N.
collection PubMed
description A 28-year-old female who underwent live donor liver transplantation 3 years prior presented after percutaneous liver biopsy with abdominal and shoulder pain, nausea, vomiting, and elevated liver enzymes. Computed tomography (CT) showed an intrahepatic and subcapsular hematoma. There was a progressive increase in liver enzymes, bilirubin, and INR and a decline in hemoglobin. Subsequent CT imaging revealed flattening of the portal vein consistent with compression by the enlarging hematoma. Liver failure ensued and the patient required urgent retransplantation. The explant demonstrated ischemic necrosis of greater than 90% of the liver parenchyma. We report this case of “Hepatic Compartment Syndrome” leading to fulminant hepatic failure.
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spelling pubmed-28525962010-04-15 Percutaneous Liver Biopsy after Living Donor Liver Transplantation Resulting in Fulminant Hepatic Failure: The First Reported Case of Hepatic Compartment Syndrome Nissen, Nicholas N. Geller, Stephen A. Klein, Andrew Colquhoun, Steve Yamini, David Tran, Tram T. Weinberg, Benjamin Winn, Julie Poordad, Fred J Transplant Case Report A 28-year-old female who underwent live donor liver transplantation 3 years prior presented after percutaneous liver biopsy with abdominal and shoulder pain, nausea, vomiting, and elevated liver enzymes. Computed tomography (CT) showed an intrahepatic and subcapsular hematoma. There was a progressive increase in liver enzymes, bilirubin, and INR and a decline in hemoglobin. Subsequent CT imaging revealed flattening of the portal vein consistent with compression by the enlarging hematoma. Liver failure ensued and the patient required urgent retransplantation. The explant demonstrated ischemic necrosis of greater than 90% of the liver parenchyma. We report this case of “Hepatic Compartment Syndrome” leading to fulminant hepatic failure. Hindawi Publishing Corporation 2010 2010-04-08 /pmc/articles/PMC2852596/ /pubmed/20396383 http://dx.doi.org/10.1155/2010/273578 Text en Copyright © 2010 Nicholas N. Nissen et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Nissen, Nicholas N.
Geller, Stephen A.
Klein, Andrew
Colquhoun, Steve
Yamini, David
Tran, Tram T.
Weinberg, Benjamin
Winn, Julie
Poordad, Fred
Percutaneous Liver Biopsy after Living Donor Liver Transplantation Resulting in Fulminant Hepatic Failure: The First Reported Case of Hepatic Compartment Syndrome
title Percutaneous Liver Biopsy after Living Donor Liver Transplantation Resulting in Fulminant Hepatic Failure: The First Reported Case of Hepatic Compartment Syndrome
title_full Percutaneous Liver Biopsy after Living Donor Liver Transplantation Resulting in Fulminant Hepatic Failure: The First Reported Case of Hepatic Compartment Syndrome
title_fullStr Percutaneous Liver Biopsy after Living Donor Liver Transplantation Resulting in Fulminant Hepatic Failure: The First Reported Case of Hepatic Compartment Syndrome
title_full_unstemmed Percutaneous Liver Biopsy after Living Donor Liver Transplantation Resulting in Fulminant Hepatic Failure: The First Reported Case of Hepatic Compartment Syndrome
title_short Percutaneous Liver Biopsy after Living Donor Liver Transplantation Resulting in Fulminant Hepatic Failure: The First Reported Case of Hepatic Compartment Syndrome
title_sort percutaneous liver biopsy after living donor liver transplantation resulting in fulminant hepatic failure: the first reported case of hepatic compartment syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852596/
https://www.ncbi.nlm.nih.gov/pubmed/20396383
http://dx.doi.org/10.1155/2010/273578
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