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DNA supercoiling and its role in DNA decatenation and unknotting
Chromosomal and plasmid DNA molecules in bacterial cells are maintained under torsional tension and are therefore supercoiled. With the exception of extreme thermophiles, supercoiling has a negative sign, which means that the torsional tension diminishes the DNA helicity and facilitates strand separ...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853108/ https://www.ncbi.nlm.nih.gov/pubmed/20026582 http://dx.doi.org/10.1093/nar/gkp1161 |