Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction

The transcriptional response driven by Hypoxia-inducible factor (HIF) is central to the adaptation to oxygen restriction. Hence, the complete identification of HIF targets is essential for understanding the cellular responses to hypoxia. Herein we describe a computational strategy based on the combi...

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Detalles Bibliográficos
Autores principales: Ortiz-Barahona, Amaya, Villar, Diego, Pescador, Nuria, Amigo, Jorge, del Peso, Luis
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853119/
https://www.ncbi.nlm.nih.gov/pubmed/20061373
http://dx.doi.org/10.1093/nar/gkp1205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853119/
https://www.ncbi.nlm.nih.gov/pubmed/20061373
http://dx.doi.org/10.1093/nar/gkp1205

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