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Waved aCGH: to smooth or not to smooth
Array-based comparative genomic hybridization (aCGH) is a powerful tool to detect genomic imbalances in the human genome. The analysis of aCGH data sets has revealed the existence of a widespread technical artifact termed as ‘waves’, characterized by an undulating data profile along the chromosome....
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853126/ https://www.ncbi.nlm.nih.gov/pubmed/20071741 http://dx.doi.org/10.1093/nar/gkp1215 |