Genetic modifiers of Hb E/β(0 )thalassemia identified by a two-stage genome-wide association study

BACKGROUND: Patients with Hb E/β(0 )thalassemia display remarkable variability in disease severity. To identify genetic modifiers influencing disease severity, we conducted a two-stage genome scan in groups of 207 mild and 305 severe unrelated patients from Thailand with Hb E/β(0 )thalassemia and no...

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Detalles Bibliográficos
Autores principales: Sherva, Richard, Sripichai, Orapan, Abel, Kenneth, Ma, Qianli, Whitacre, Johanna, Angkachatchai, Vach, Makarasara, Wattanan, Winichagoon, Pranee, Svasti, Saovaros, Fucharoen, Suthat, Braun, Andreas, Farrer, Lindsay A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853425/
https://www.ncbi.nlm.nih.gov/pubmed/20353593
http://dx.doi.org/10.1186/1471-2350-11-51

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