Cargando…

Efficient gene delivery and silencing of mouse and human pancreatic islets

BACKGROUND: In view of the importance of beta cells in glucose homeostasis and the profound repercussions of beta cell pathology on human health, the acquisition of tools to study pancreatic islet function is essential for the design of alternative novel therapies for diabetes. One promising approac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lefebvre, Bruno, Vandewalle, Brigitte, Longue, Justine, Moerman, Ericka, Lukowiak, Bruno, Gmyr, Valery, Maedler, Kathrin, Kerr-conte, Julie, Pattou, François
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Methodology article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853492/ https://www.ncbi.nlm.nih.gov/pubmed/20353585 http://dx.doi.org/10.1186/1472-6750-10-28

Ejemplares similares

Primary Graft Function, Metabolic Control, and Graft Survival After Islet Transplantation
por: Vantyghem, Marie-Christine, et al.
Publicado: (2009)

Adaptive changes of human islets to an obesogenic environment in the mouse
por: Gargani, S., et al.
Publicado: (2012)

The challenge of HLA donor specific antibodies in the management of pancreatic islet transplantation: an illustrative case-series
por: Maanaoui, Mehdi, et al.
Publicado: (2022)

The Class I Histone Deacetylase Inhibitor MS-275 Prevents Pancreatic Beta Cell Death Induced by Palmitate
por: Plaisance, Valérie, et al.
Publicado: (2014)

Coxsackievirus-B4 Infection of Human Primary Pancreatic Ductal Cell Cultures Results in Impairment of Differentiation into Insulin-Producing Cells
por: Bertin, Antoine, et al.
Publicado: (2019)

Degradation of cAMP-Responsive Element–Binding Protein by the Ubiquitin-Proteasome Pathway Contributes to Glucotoxicity in β-Cells and Human Pancreatic Islets
por: Costes, Safia, et al.
Publicado: (2009)

Erratum. Ten-Year Outcome of Islet Alone or Islet After Kidney Transplantation in Type 1 Diabetes: A Prospective Parallel-Arm Cohort Study. Diabetes Care 2019;42:2042–2049
por: Vantyghem, Marie-Christine, et al.
Publicado: (2020)

JNK3 Is Required for the Cytoprotective Effect of Exendin 4
por: Ezanno, Hélène, et al.
Publicado: (2014)

MST1 is a novel regulator of apoptosis in pancreatic beta-cells
por: Ardestani, Amin, et al.
Publicado: (2014)

Simultaneous silencing of multiple RB and p53 pathway members induces cell cycle reentry in intact human pancreatic islets
por: Tamaki, Stanley, et al.
Publicado: (2014)

Effects of subtotal pancreatectomy and long‐term glucose and lipid overload on insulin secretion and glucose homeostasis in minipigs
por: Goutchtat, Rébecca, et al.
Publicado: (2023)

Exploring G Protein-Coupled Receptor Signaling in Primary Pancreatic Islets
por: Röthe, Juliane, et al.
Publicado: (2020)

Coxsackievirus-B4 Infection Can Induce the Expression of Human Endogenous Retrovirus W in Primary Cells
por: Dechaumes, Arthur, et al.
Publicado: (2020)

Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL
por: Plaisance, Valérie, et al.
Publicado: (2016)

Glucose Regulates m(6)A Methylation of RNA in Pancreatic Islets
por: Bornaque, Florine, et al.
Publicado: (2022)

Genetic regulation of RNA splicing in human pancreatic islets
por: Atla, Goutham, et al.
Publicado: (2022)

Macrophage-associated pro-inflammatory state in human islets from obese individuals
por: He, Wei, et al.
Publicado: (2019)

GLP-2 Is Locally Produced From Human Islets and Balances Inflammation Through an Inter-Islet-Immune Cell Crosstalk
por: He, Wei, et al.
Publicado: (2021)

Protection of Pancreatic Islets Using Theranostic Silencing Nanoparticles in a Baboon Model of Islet Transplantation
por: Pomposelli, Thomas, et al.
Publicado: (2020)

Siglec-7 restores β-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes
por: Dharmadhikari, Gitanjali, et al.
Publicado: (2017)

Epithelial-Mesenchymal Transition in Cells Expanded In Vitro from Lineage-Traced Adult Human Pancreatic Beta Cells
por: Russ, Holger A., et al.
Publicado: (2009)

Method: low-cost delivery of the cotton leaf crumple virus-induced gene silencing system
por: Tuttle, John Richard, et al.
Publicado: (2012)

Hypertonic sodium lactate improves fluid balance and hemodynamics in porcine endotoxic shock
por: Duburcq, Thibault, et al.
Publicado: (2014)

Deathly triangle for pancreatic β-cells: Hippo pathway-MTORC1-autophagy
por: Ardestani, Amin, et al.
Publicado: (2021)

Comment on: Saisho et al. β-Cell Mass and Turnover in Humans: Effects of Obesity and Aging. Diabetes Care 2013;36:111–117
por: Gargani, Sofia A., et al.
Publicado: (2013)

Angiopoetin-2 Signals Do Not Mediate the Hypervascularization of Islets in Type 2 Diabetes
por: Shah, Payal, et al.
Publicado: (2016)

In vivo silencing of alpha-synuclein using naked siRNA
por: Lewis, Jada, et al.
Publicado: (2008)

Correction: Angiopoetin-2 Signals Do Not Mediate the Hypervascularization of Islets in Type 2 Diabetes
por: Shah, Payal, et al.
Publicado: (2023)

Cassava geminivirus agroclones for virus-induced gene silencing in cassava leaves and roots
por: Lentz, Ezequiel Matias, et al.
Publicado: (2018)

Characterizing virus-induced gene silencing at the cellular level with in situ multimodal imaging
por: Burkhow, Sadie J., et al.
Publicado: (2018)

Rapid, high efficiency virus-mediated mutant complementation and gene silencing in Antirrhinum
por: Tan, Ying, et al.
Publicado: (2020)

Neuromedin U uses Gα(i2) and Gα(o) to suppress glucose-stimulated Ca(2+) signaling and insulin secretion in pancreatic β cells
por: Zhang, Weidong, et al.
Publicado: (2021)

An effective virus-based gene silencing method for functional genomics studies in common bean
por: Díaz-Camino, Claudia, et al.
Publicado: (2011)

A cassava common mosaic virus vector for virus-induced gene silencing in cassava
por: Tuo, Decai, et al.
Publicado: (2021)

Foxtail mosaic virus-induced gene silencing (VIGS) in switchgrass (Panicum virgatum L.)
por: Tiedge, Kira, et al.
Publicado: (2022)

A CRISPR interference strategy for gene expression silencing in multiple myeloma cell lines
por: Escrivá-Fernández, Josep, et al.
Publicado: (2023)

Type 2 Diabetes Susceptibility Gene Expression in Normal or Diabetic Sorted Human Alpha and Beta Cells: Correlations with Age or BMI of Islet Donors
por: Kirkpatrick, Clare L., et al.
Publicado: (2010)

CRISPR/Cas9-mediated knockin of IRES-tdTomato at Ins2 locus reveals no RFP-positive cells in mouse islets
por: Zhou, Xueling, et al.
Publicado: (2023)

Visualization of plant viral suppressor silencing activity in intact leaf lamina by quantitative fluorescent imaging
por: Stephan, Dirk, et al.
Publicado: (2011)

Protocol: using virus-induced gene silencing to study the arbuscular mycorrhizal symbiosis in Pisum sativum
por: Grønlund, Mette, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_k67kvd0k4oo6ib0kgn725fpp0a