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Arginylation Regulates Intracellular Actin Polymer Level by Modulating Actin Properties and Binding of Capping and Severing Proteins

Actin arginylation regulates lamella formation in motile fibroblasts, but the underlying molecular mechanisms are unknown. To understand how arginylation affects the actin cytoskeleton, we investigated the biochemical properties and the structural organization of actin filaments in wild-type and arg...

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Detalles Bibliográficos
Autores principales: Saha, Sougata, Mundia, Maureen M., Zhang, Fangliang, Demers, Ryan W., Korobova, Farida, Svitkina, Tatyana, Perieteanu, Alex A., Dawson, John F., Kashina, Anna
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854093/
https://www.ncbi.nlm.nih.gov/pubmed/20181827
http://dx.doi.org/10.1091/mbc.E09-09-0829