GLUT4 Is Sorted to Vesicles Whose Accumulation Beneath and Insertion into the Plasma Membrane Are Differentially Regulated by Insulin and Selectively Affected by Insulin Resistance

Insulin stimulates glucose transport by recruiting the GLUT4 glucose transporter to the plasma membrane. Here we use total internal reflection fluorescence microscopy to show that two trafficking motifs of GLUT4, a FQQI motif and a TELE-based motif, target GLUT4 to specialized vesicles that accumula...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiong, Wenyong, Jordens, Ingrid, Gonzalez, Eva, McGraw, Timothy E.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854095/
https://www.ncbi.nlm.nih.gov/pubmed/20181829
http://dx.doi.org/10.1091/mbc.E09-08-0751

Ejemplares similares

Ejemplares similares