Cargando…
An Excitatory Loop with Astrocytes Contributes to Drive Neurons to Seizure Threshold
Seizures in focal epilepsies are sustained by a highly synchronous neuronal discharge that arises at restricted brain sites and subsequently spreads to large portions of the brain. Despite intense experimental research in this field, the earlier cellular events that initiate and sustain a focal seiz...
Autores principales: | Gómez-Gonzalo, Marta, Losi, Gabriele, Chiavegato, Angela, Zonta, Micaela, Cammarota, Mario, Brondi, Marco, Vetri, Francesco, Uva, Laura, Pozzan, Tullio, de Curtis, Marco, Ratto, Gian Michele, Carmignoto, Giorgio |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854117/ https://www.ncbi.nlm.nih.gov/pubmed/20405049 http://dx.doi.org/10.1371/journal.pbio.1000352 |
Ejemplares similares
-
Ictal but Not Interictal Epileptic Discharges Activate Astrocyte Endfeet and Elicit Cerebral Arteriole Responses
por: Gómez-Gonzalo, Marta, et al.
Publicado: (2011) -
Calcium Signals in Astrocyte Microdomains, a Decade of Great Advances
por: Lia, Annamaria, et al.
Publicado: (2021) -
Rescue of astrocyte activity by the calcium sensor STIM1 restores long-term synaptic plasticity in female mice modelling Alzheimer’s disease
por: Lia, Annamaria, et al.
Publicado: (2023) -
The inflammatory molecules IL-1β and HMGB1 can rapidly enhance focal seizure generation in a brain slice model of temporal lobe epilepsy
por: Chiavegato, Angela, et al.
Publicado: (2014) -
Computational model of neuron-astrocyte interactions during focal seizure generation
por: Reato, Davide, et al.
Publicado: (2012)