Spadin, a Sortilin-Derived Peptide, Targeting Rodent TREK-1 Channels: A New Concept in the Antidepressant Drug Design

Current antidepressant treatments are inadequate for many individuals, and when they are effective, they require several weeks of administration before a therapeutic effect can be observed. Improving the treatment of depression is challenging. Recently, the two-pore domain potassium channel TREK-1 h...

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Detalles Bibliográficos
Autores principales: Mazella, Jean, Pétrault, Olivier, Lucas, Guillaume, Deval, Emmanuel, Béraud-Dufour, Sophie, Gandin, Carine, El-Yacoubi, Malika, Widmann, Catherine, Guyon, Alice, Chevet, Eric, Taouji, Said, Conductier, Grégory, Corinus, Alain, Coppola, Thierry, Gobbi, Gabriella, Nahon, Jean-Louis, Heurteaux, Catherine, Borsotto, Marc
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854129/
https://www.ncbi.nlm.nih.gov/pubmed/20405001
http://dx.doi.org/10.1371/journal.pbio.1000355

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