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Tumorigenic Properties of Iron Regulatory Protein 2 (IRP2) Mediated by Its Specific 73-Amino Acids Insert

Iron regulatory proteins, IRP1 and IRP2, bind to mRNAs harboring iron responsive elements and control their expression. IRPs may also perform additional functions. Thus, IRP1 exhibited apparent tumor suppressor properties in a tumor xenograft model. Here we examined the effects of IRP2 in a similar...

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Detalles Bibliográficos
Autores principales:	Maffettone, Carmen, Chen, Guohua, Drozdov, Ignat, Ouzounis, Christos, Pantopoulos, Kostas
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854138/ https://www.ncbi.nlm.nih.gov/pubmed/20405006 http://dx.doi.org/10.1371/journal.pone.0010163

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