Manipulating Heat Shock Factor-1 in Xenopus Tadpoles: Neuronal Tissues Are Refractory to Exogenous Expression

BACKGROUND: The aging related decline of heat shock factor-1 (HSF1) signaling may be causally related to protein aggregation diseases. To model such disease, we tried to cripple HSF1 signaling in the Xenopus tadpole. RESULTS: Over-expression of heat shock factor binding protein-1 did not inhibit the...

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Detalles Bibliográficos
Autores principales: Dirks, Ron P., van Geel, Remon, Hensen, Sanne M. M., van Genesen, Siebe T., Lubsen, Nicolette H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854154/
https://www.ncbi.nlm.nih.gov/pubmed/20405018
http://dx.doi.org/10.1371/journal.pone.0010158

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