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N(3)-o-toluyl-fluorouracil inhibits human hepatocellular carcinoma cell growth via sustained release of 5-FU
PURPOSE: N(3)-o-toluyl-fluorouracil (TFU), the prodrug of 5-fluorouracil (5-FU), is the metabolite of N(1)-acetyl-N(3)-o-toluyl-fluorouracil (atofluding). In the present study, we aimed to evaluate the efficacy of TFU on the inhibition of human hepatocellular carcinoma cells via sustained release of...
Autores principales: | Zhang, Xiaofan, Zhong, Julia Li, Liu, Wei, Gao, Zuhua, Xue, Xia, Yue, Pan, Wang, Limei, Zhao, Cuirong, Xu, Wenfang, Qu, Xianjun |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854362/ https://www.ncbi.nlm.nih.gov/pubmed/19756602 http://dx.doi.org/10.1007/s00280-009-1128-0 |
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