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Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology
During myofibril assembly, thin filament lengths are precisely specified to optimize skeletal muscle function. Tropomodulins (Tmods) are capping proteins that specify thin filament lengths by controlling actin dynamics at pointed ends. In this study, we use a genetic targeting approach to explore th...
Autores principales: | Gokhin, David S., Lewis, Raymond A., McKeown, Caroline R., Nowak, Roberta B., Kim, Nancy E., Littlefield, Ryan S., Lieber, Richard L., Fowler, Velia M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854367/ https://www.ncbi.nlm.nih.gov/pubmed/20368620 http://dx.doi.org/10.1083/jcb.201001125 |
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