Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

Epithelial paracellular barrier function, determined primarily by tight junction permeability, is frequently disrupted in disease. In the intestine, barrier loss can be mediated by tumor necrosis factor (α) (TNF) signaling and epithelial myosin light chain kinase (MLCK) activation. However, TNF indu...

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Detalles Bibliográficos
Autores principales: Marchiando, Amanda M., Shen, Le, Graham, W. Vallen, Weber, Christopher R., Schwarz, Brad T., Austin, Jotham R., Raleigh, David R., Guan, Yanfang, Watson, Alastair J.M., Montrose, Marshall H., Turner, Jerrold R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854371/
https://www.ncbi.nlm.nih.gov/pubmed/20351069
http://dx.doi.org/10.1083/jcb.200902153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854371/
https://www.ncbi.nlm.nih.gov/pubmed/20351069
http://dx.doi.org/10.1083/jcb.200902153

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